Modulation of miRNA expression in aged rat hippocampus by buttermilk and krill oil
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چکیده
منابع مشابه
Alteration in the Expression of Alzheimer's-Related Genes in Rat Hippocampus by Exercise and Morphine Treatments
Introduction: Alzheimer's disease is a progressive brain disorder, which slowly eliminates memory and intellectual ability and eventually destroys the ability to carry out the simple tasks. β amyloid plaque and neurofibrillary tangles are two important signatures of this disease, which caused by mutant in Tau, BACE1, and APP genes. They could be important targets for treatment of Alzheimer's di...
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BACKGROUND Aging is associated with the gradual cognitive decline and shows the typical senile plaque formation in the brain, which results from the aggregation of beta amyloid (Aβ) peptide following the abnormal proteolytic processing of amyloid precursor protein (APP) by β-secretase (BACE1) and γ-secretase. Accumulating evidence indicates that several microRNAs (miRNAs) are involved in the Al...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2018
ISSN: 2045-2322
DOI: 10.1038/s41598-018-22148-5